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New Delhi, Nov. 26 — Caliper Life Sciences Inc received patent for a method of identifying the presence of a subsequence of nucleotides in a target nucleic acid and an assay system on Sept. 12, 2008. The patent number issued by the Indian Patent Office is 221302.

Caliper Life Sciences Inc had filed patent application number 2962/CHENP/2005 for a method of identifying the presence of a subsequence of nucleotides in a target nucleic acid and an assay system on Nov. 10, 2005. The inventor of the patent is Nikiforov Theo T.

The International classification number is C12Q1/37.

The PCT International application number of the patent is PCT/US00/13293 and the application was filed on May 11, 2000.

According to the Controller General of Patents, Designs Trade Marks, “A method of identifying the presence of a subsequence of nucleotides in a target nucleic acid and an assay system The present invention relates to a method of identifying the presence of a subsequence of nucleotides in a target nucleic acid, the method comprising: contacting the target nucleic acid sequence with a substantially uncharged or positively charged, fluorescently labeled nucleic acid analog in a first reaction mixture, the nucleic acid analog being complementary to the subsequence whereby the nucleic acid analog is capable of specifically hybridizing to the subsequence to form a first hybrid; contacting the first reaction mixture with a polyion; and comparing a level of fluorescence polarization of the first reaction mixture in the presence of the polyion to a level of fluorescence polarization of the nucleic acid analog in the absence of the target nucleic acid sequence, an increase in the level of fluorescence polarization indicating a presence of the first hybrid. The invention also relates to an assay system for the same.”

About the Company

Caliper Life Sciences (NASDAQ: CALP) is a leading provider of cutting-edge technologies enabling researchers in the life sciences to create life-saving and enhancing medicines and diagnostic tests more quickly and efficiently. Caliper has compiled numerous best-in-class solutions and is aggressively innovating new technologies to bridge the gaps that exist in bringing in vitro assays to in vivo results and ultimately into cures for human disease. With a keen focus on clinically-relevant experimentation, Caliper’s portfolio of offerings includes state-of-the-art microfluidics, lab automation liquid handling, optical imaging technologies, and discovery development outsourcing solutions.


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